Jason Sehorn – New York Giants
After back-to-back successful seasons with the Giants, Sehorn sustained a crippling knee injury, tearing his MCL and ACL. He returned the following season and played for five more but nothing like the true player he once was. He eventually retired in 2003 and is currently a panelist for Fox Sports Net.
Joel Przybilla – Portland Trail Blazers
In 2009, in a game against the Mavericks, Joel Przybilla ruptured his Patella tendon as he came down from a rebound, landing on his knee rather awkwardly. That’s all it took. Days later, he underwent surgery, missing the rest of season. He officially retired in 2014.